Diseases & Disorders

  • Acute disseminated encephalomyelitis (ADEM) is an inflammation in the brain and spinal cord that damages the protective covering of nerve fibers.
  • Addison's disease is a chronic disorder in which the adrenal glands do not produce sufficient steroid hormones causing abdominal pain, weakness and skin discoloration.
  • Alopecia or Alopecia Areata(AA) results in loss of hair on scalp, beard or the skin as the immune system attacks the hair follicles and slows down hair production.
  • Anklosing spondylitis is a type of arthritis that affects the spine and is characterized by inflammation and stiffness from the neck down to the lower back.
  • Autoimmune chronic active hepatitis (CAH), or autoimmune hepatitis, is a chronic inflammatory disease of the liver that occurs when the body's immune system attacks cells of the liver.
  • Autoimmune hemolytic anemia occurs when antibodies directed against the person's own red blood cells cause them to burst, leading to insufficient plasma concentration.
  • Autoimmune pancreatitis (AIP) is a chronic inflammation of the pancreas. Symptoms usually include jaundice, weight loss, abdominal pain or itching.
  • Autoimmune thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necessary for prevention and control of bleeding.
  • Autoimmune neutropenia, also known as autoimmune leukopenia, is a blood disorder in which a person's antibodies attack and destroy white blood cells that fight off infection.
  • Autoimmune Inner Ear Disease (AIED) is an inflammatory condition of the inner ear causing hearing loss and tinnitus. It occurs when the body's immune system attacks cells in the inner ear that are mistaken for a virus or bacteria
  • Antiphospholipid Syndrome (APS), sometimes called Hughes syndrome, is a disorder characterized by elevated levels of antibodies that leads to formation of blood clots in arteries or veins.
  • Autoimmune Lymphoproliferative Syndrome (ALPS) is a disorder where unusually high numbers of white blood cells called lymphocytes accumulate in the lymph nodes, liver, and spleen leading to enlargement of these organs.
  •  Behcet's syndrome is a disease that causes inflammation of the blood vessels throughout the body.
  • Bullus pemphigoid is a skin disease characterized by blisters and large red welts and hives.
  • Castleman's Disease is a disorder that affects the lymph nodes of the body and is characterized by an overgrowth of lymphatic cells.
  • Celiac disease is a digestive disorder that results in damage to the lining of the small intestine when foods with gluten are eaten.
  • Central nervous system (CNS) vasculitis is an inflammation of blood vessel walls in the brain or spine
  • Cogan's Syndrome is a disorder characterized by inflammation of the front of the eye and often fever, weakness, and episodes of dizziness and hearing loss.
  • Churg-Strauss Syndrome (CSS), or Alergic Granulomatosis Angiitis is an autoimmune disease characterized by inflammation of the small to medium sized blood vessels.
  • Allergic Granulomatosis Angiitis, is an inflammation of the small to medium blood vessels.
  • Chronic bullous disease is a skin condition which results in clusters of blisters developing in rings often on the face or genitals.
  • Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) is a disorder of the peripheral nerves characterized by gradually increasing weakness of the legs and, to a lesser extent, the arms.
  • Cictricial  pemphigoid (CP) is characterized by small blisters or erosions on any mucous membrane including the nose, mouth, eyes, esophagus, larynx, urethra and anus.
  • Central Nervous System Vasculitis inflames the blood vessels in the brain and spinal cord.
  • Celiac disease damages the lining of the small intestine and prevents it from absorbing certain foods. The damage is due to a reaction from eating gluten.
  • Crohn's disease is a bowel disease with persistent inflammation of the lining or wall of the gastrointestinal tract.
  • Cryoglobulinemia is part of a group of diseases that causes damage and inflammation of the blood vessels throughout the body (vasculitis).
  • Dermatomyositis is a connective-tissue disease related to polymyositis (PM) that is characterized by inflammation of the muscles and the skin.
  • Dermatitis herpetiformis (DH), or Duhring's disease, is a blistering skin diseases caused by gluten intolerance and therefore is associated with Crohn's disease.
  • Diabetestype 1 (T1D) is an autoimmune disease in which a person's pancreas stops producing insulin, a hormone that enables people to get energy from food.
  • Discoid lupus erythematosus (DLE) is a chronic dermatological disease that can lead to scarring, hair loss and changes to the skin.
  • Duhring's disease, or dermatitis herpetiformis,is a blistering skin diseases caused by gluten intolerance and therefore is associated with Crohn's disease.
  • Endometriosis is a condition where endometrial tissue (cells that normally grow only inside the uterus) grow in abnormal ways and in the wrong places.
  • Epidermolysis bullosa acquisita (EBA) is a chronic autoimmune blistering disease of the skin and mucus membranes.
  • Erythema nodosum is a skin condition that results in reddish, painful lumps most commonly on the front of the legs below the knees. In some cases it can result from autoimmune issues.
  • Evans syndrome is an autoimmune disorder in which the body makes antibodies that destroy the red blood cells, platelets and white blood cells.
  • Giant Cell Arteritis a disorder that causes inflammation of arteries of the scalp, neck, and arms.
  • Goodpasture syndrome is a serious autoimmune disease that attacks the lungs or the kidneys.
  • Graft-versus-host disease is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted donor cells attack the transplant recipient's body.
  • Graves' Disease is an autoimmune disease in which the patient's own immune system attacks the thyroid gland, causing it to produce too much of a thyroid hormone which controls metabolism.
  • Gullain-Barre syndrome occurs when the immune system attacks the peripheral nervous system leading to nerve inflammation that causes muscle weakness and other symptoms.
  • Hashimoto's thyroiditis is a chronic inflammation of the thyroid, which often leads to an underactive thyroid gland (hypothyroidism).
  • Immune-mediated infertility is a condition in whichabnormal immune function affects fertility.
  • Inflammatory bowel disease refers to chronic diseases of the bowel such as ulcerative colitis and Crohn 's disease.
  • Insulin-dependent diabetes mellitus is the autoimmune form of diabetes and often arises in childhood. It is caused by the destruction of cells in the pancreas that produce insulin, the hormone that helps regulate glucose levels in the blood.
  • Interstitial Cystitis (IC) is a disorder where the space between the bladder lining and the bladder muscle is chronically inflamed, leading to pain and frequent urination.
  • Isolated vasculitis of the central nervous system also known as primary angiitis of the central nervous system is a condition where the body's immune system attacks arteries of the brain, causing inflammation (swelling).
  • Isaacs' Syndrome or Neuromyotonia is a disorder characterized by twitching muscles, muscle stiffness and sweating.
  • Juvenile Dermatomyositis is a inflammatory disease of the muscle (myositis), skin and blood vessels that affects children.
  • Kawasaki disease (KD) is a sudden and time-limited illness that causes medium-sized blood vessels throughout the body to become inflamed. Largely affects infants and young children.
  • Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder characterized by muscle weakness of the limbs.
  • Lichen Planus is a common autoimmune skin condition in which antibodies attack the skin, mucous membranes, hair and nails.
  • Linear IgA disease is a blistering disorder.
  • Lupus is a chronic inflammatory disease that often affects various parts of the body.
  • Meniere's Disease is a disorder of the inner ear that can affect hearing and balance.
  • Microscopic Polyangiitis(MPA) is a disorder that causes blood vessel inflammation (vasculitis), which can lead to organ damage.
  • Mixed connective tissue disease (MCTD) [also called Sharp's Syndrome] is an autoimmune disorder that causes overlapping features of three connective tissue disorders: lupus, scleroderma, and polymyositis. People with MCTD experience symptoms of each of these three diseases.
  • Myasthenia gravis is a chronic condition that causes muscles to tire and weaken easily.
  • Multiple Sclerosis attacks thecentral nervous system interfering with the nerves system signals, causing neurological symptoms.
  • Multifocal motor neuropathy is a nerve disease that affects the nerves to the muscles and thus causes weakness and cramping in muscles.
  • Necrotizing vascolitides is a condition that involves inflammation of the blood vessel walls.
  • Neuromyotonia or Isaac's syndrome is a disorder characterized by twitching muscles, muscle stiffness and sweating.
  • Opsoclonus-myoclonus syndrome is a neurological disorder with onset in early childhood that causes jerky, uncoordinated movements of the eyes and body.
  • Paraneoplastic neurologic disorders are a group of rare degenerative conditions that are triggered by a person's immune system response to a cancerous tumor.
  • Pemphigus vulgaris is a serious skin disease that involves painful sores and blisters on the skin and in the mouth.
  • Pemphigus follaceus (PF) is a blistering disease of the skin and mucous membranes. It is generally a benign variety of pemphigus.
  • Pemphigoid gestationis(PG) is an autoimmune blistering disease that occurs during pregnancy.
  • Pernicious anemia is a chronic illness in which the body can't make enough healthy red blood cells because of lack of vitamin B12.
  • Paraneoplastic pemphigus (PNP) is a life threatening blistering disease with painful sores on the lips, mouth, and the esophagus and is usually associated with cancer.
  • Polyangiitis is a disorder that causes blood vessel inflammation that can lead to organ damage.
  • Polyarteritis nodosa (PAN) is a disease with inflammation of medium & small-sized arteries, which become swollen and damaged.
  • Polyglandular autoimmune syndrome (PAS) is an inherited disease in which the body's immune system mistakenly attacks healthy cells, notably the glands that produce the body's hormones.
  • Polymyositisis a relativelyuncommon inflammatory disease that leads to muscle weakness, swelling (inflammation), tenderness, and damage.
  • Polymyalgia Rheumatica is an inflammatory disorder involving pain and stiffness in the shoulder and also in the hip.
  • Primary biliary Cirrhosis(PBC) (also called Hanot Syndrome) is a chronic liver disease in which the body destroys the cells lining the bile ducts in the liver.
  • Primary sclerosing cholangitis (PSC) is a chronic disease that slowly damages the bile ducts inside and outside the liver.
  • Psoriasis is a common skin condition that causes skin redness and irritation.
  • Raynaud's phenomenon is a condition in which blood flow to the surface tissue of the hands and feet is temporarily decreased causing them to feel cold or numb. Usually associated with other autoimmune diseases.
  • Reactive Arthritis, formerly known as Reiter's syndrome, is a painful form of inflammatory arthritis that develops in reaction to an infection by bacteria.
  • Rheumatoid arthritis(RA) is a chronic systemic inflammatory disorder that may affect many tissues and organs, but primarily attacks flexible joints.
  • Sarcoidosis is an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands.
  • Sjogren's syndrome is an inflammatory disease that can affect many different parts of the body, but most often it affects the tear and saliva glands.
  • Stiff-person syndromeor Moersch-Woltmann syndrome, is a disease of severe progressive muscle stiffness of the spine and lower extremities
  • Systemic lupus erythematosus (referred to as SLE or Lupus) is a chronic inflammatory disease that can affect various parts of the body.
  • Scleroderma (also known as systemic sclerosis) is a disease affecting the skin and other organs of the body.
  • Temporal arteritis (or giant cell arteritis (GCV)) is an inflammatory condition affecting the medium-sized blood vessels that supply the head, eyes, and optic nerves.
  • Takayasu's arteritis is a rheumatic disease that causes the aorta and its branches to become inflamed.
  • Thromboangiitis obliterans(also known as Buerger's disease or Presenile gangrene) is an inflammation and clotting of the veins and arteries in the hands and feet. The condition is strongly associated with heavy tobacco use.
  • Vasculitis is a group of disorders that destroy blood vessels by inflammation.
  • Vitiligo is a skin condition in which there is a loss of brown color (pigment) from areas of skin, resulting in irregular white patches.
  • Wegener's granulomatosis is a disorder in which blood vessels become inflamed, making it hard for blood to flow.