Pemphigus foliaceus is an autoimmune blistering disease of the skin and mucous membranes with characteristic lesions that are scaly and crusted. Pemphigus foliaceus (PF) is a relatively benign form of pemphigus.
Pemphigus foliaceus is characterized by blistering lesions on otherwise healthy-looking skin. Blisters tend to form when the skin is rubbed.
Pemphigus foliaceus is generally confined to the skin. Those affected are usually otherwise in good health. Small fluid-filled blisters first form on the trunk. Because they form in the upper layers of the skin, they rupture very easily and only small ulcers may be seen. On the face, scalp and upper trunk the lesions are often scaly and crusty on a red and inflamed base. A burning sensation or localized pain may be felt.
Pemphigus foliaceus affects people of all races, age and sex. It appears most commonly between the ages of 50-60 years
Spontaneous remission may occur in some patients while in others the problem may persist for several years. The primary aim of treatment is to prevent new areas from developing infections and promote healing of affected areas. Topical treatment with corticosteroids and antibiotics is usually all that is necessary for mild cases of pemphigus foliaceus.